Summary: Drug-tolerant persister (DTP) cells have attracted significant interest, given their predominant role in treatment failure.In this respect, DTP cells reportedly survive after anticancer drug exposure, and their DNA repair mechanisms are altered to enhance adaptive mutation, accounting for the emergence of drug-resistant mutations.DTP cells
Crop host-pathogen interaction have been a main issue for decades, in particular for food security.In this paper, we focus on the modeling and long term behavior of soil-borne pathogens.We first develop a new compartmental temporal model, which exhibits bi-stable asymptotical dynamics.To investigate the long term behavior, we use LaSalle Invariance
Power electronic converters, together with their loads, sources, and controls, form a coupled system that includes many nonlinear interactions, for instance due to pulse-width modulation (PWM) and feedback control.In this paper we develop a complete, nonlinear modeling approach for 1/6th Accessory Set voltage-source inverters in the frequency domai
BackgroundMany countries have introduced legislations for public smoking bans to reduce the harmful effects of exposure to tobacco smoke.Smoking bans cause significant reductions in admissions for acute coronary syndromes but their impact on respiratory diseases is unclear.In Geneva, Switzerland, two popular votes led to a stepwise implementation o
Abstract The drag loss behavior of a disengaged wet clutch is influenced, among other things, by the movement of the plates.Therefore, knowledge about the plate movement is essential for investigating and optimizing the drag loss behavior.This paper presents a methodology for image-based measurement of plate movement in disengaged wet clutches.A dr